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Roxatidine Acetate CAS Registry Number: 78628-28-1 醋酸罗沙替丁

CAS Name: 2-(Acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide
Additional Names: aceroxatidine
Percent Composition: C 65.49%, H 8.10%, N 8.04%, O 18.37%

📌 参考资料/链接：
Literature References: Histamine H2-receptor antagonist. Prepn and anti-ulcerative activity: K. Shibata et al., EP 24510; eidem, US 4293557 (both 1981 to Teikoku Hormone). Pharmacology in animals: M. Tarutani et al., Arzneim.-Forsch. 35, 703 (1985). Comparison with cimetidine of effect on gastric acid secretion and ulcer formation in animals: eidem, ibid. 844. Metabolism in humans: S. Honma et al., Oyo Yakuri 30, 555 (1985); C.A. 104, 61453n (1985).

📄 详细内容

Properties: mp 59-60°. LD50 orally in male mice: 1000 mg/kg (Shibata).
Melting point: mp 59-60°
Toxicity data: LD50 orally in male mice: 1000 mg/kg (Shibata)
Derivative Type: Hydrochloride
CAS Registry Number: 93793-83-0
Additional Names: PifatidineTrademarks: Altat (Teikoku Hormone); Gastralgin (De Angeli); Neo H2 (Boehringer, Ing.); Roxit (Aventis)
Percent Composition: C 59.29%, H 7.59%, N 7.28%, O 16.63%, Cl 9.21%
Properties: mp 145-146°.
Melting point: mp 145-146°
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Histamine H2-Receptor Antagonist.
产品链接: 78628-28-1››

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