网站主页>>>项目整合精选>>>项目整合精选>>> a -Estradiol CAS Registry Number: 57-91-0 17α-雌二醇

a -Estradiol CAS Registry Number: 57-91-0 17α-雌二醇


CAS Name: (17a)-Estra-1,3,5(10)-triene-3,17-diol
Additional Names: 1,3,5-estratriene-3,17a-diol; 3,17-dihydroxyestratriene
Percent Composition: C 79.37%, H 8.88%, O 11.75%
📌 参考资料/链接:
Literature References: Has been isolated from pregnancy urine of mares. Prepn from b-estradiol by inversion of the hydroxyl group at C-17 after tosylation: Allais, Hoffmann, US 2835681 (1958).

📄 详细内容


Properties: Needles with ½H2O from 80% alcohol, mp 220-223°. [a]D20 +53 to +56° (c = 0.9 in dioxane). Not precipitated by digitonin (in 80% alcoholic soln). Soluble in alcohol, acetone, aq alkalies. One gram dissolves in more than 100 ml of boiling benzene. Slightly sol in ether, chloroform. Insol in water, aq dil acids.
Melting point: mp 220-223°
Optical Rotation: [a]D20 +53 to +56° (c = 0.9 in dioxane)
Derivative Type: Diacetate
Percent Composition: C 74.13%, H 7.92%, O 17.95%
Properties: mp 140-142°.
Melting point: mp 140-142°
Derivative Type: 3-Benzoate
Percent Composition: C 79.75%, H 7.50%, O 12.75%
Properties: mp 156-157°; also reported as polymorphous: I, mp 63°; II, mp 153°; III, mp 158°.
Melting point: mp 156-157°; also reported as polymorphous: I, mp 63°; II, mp 153°; III, mp 158°
产品链接: 57-91-0››