Flubendazole CAS Registry Number: 31430-15-6 氟苯咪唑
CAS Name: [5-(4-Fluorobenzoyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Additional Names: 5-(p-fluorobenzoyl)-2-benzimidazolecarbamic acid methyl esterTrademarks: Flubenol (J J); Flumoxal (Janssen); Fluvermal (Janssen)
Percent Composition: C 61.34%, H 3.86%, F 6.06%, N 13.41%, O 15.32%
📌 参考资料/链接：
Literature References: Fluoro analog of mebendazole, q.v. Prepn: J. L. H. Van Gelder et al., DE 2029637; eidem, US 3657267 (1971, 1972 both to Janssen); A. H. M. Raeymaekers et al., Arzneim.-Forsch. 28, 586 (1978). Pharmacological, biological properties: D. Thienpont et al., ibid. 605. Anthelmintic activity in rats: O. Vanparijs et al., Vet. Parasitol. 5, 237 (1979); in pigs: E. Telléz-Giron et al., Am. J. Trop. Med. Hyg. 30, 135 (1981).
📄 详细内容
Properties: Crystals, mp 260°. LD50 in mice, rats, guinea pigs (mg/kg): 2560 orally (Thienpont).
Melting point: mp 260°
Toxicity data: LD50 in mice, rats, guinea pigs (mg/kg): 2560 orally (Thienpont)
Therap-Cat-Vet: Anthelmintic.
产品链接: 31430-15-6››