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Pazufloxacin CAS Registry Number: 127045-41-4 帕珠沙星

CAS Name: (3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acidPercent Composition: C 60.37%, H 4.75%, F 5.97%, N 8.80%, O 20.11%

📌 参考资料/链接：
Literature References: Fluorinated quinolone. Prepn: H. Narita et al., DE 3913245; eidem, US 4990508 (1989, 1991 both to Toyama). Synthesis: Y. Todo et al., Chem. Pharm. Bull. 42, 2569 (1994). Antimicrobial activity: Y. Fukuoka et al., Antimicrob. Agents Chemother. 37, 384 (1993).

📄 详细内容

Properties: Crystals, mp 269-271.5°. [a]D25 -88.0° (c = 0.5 in 0.05N aq NaOH). LD50 i.v. in male mice: 500 mg/kg (Todo).
Melting point: mp 269-271.5°
Optical Rotation: [a]D25 -88.0° (c = 0.5 in 0.05N aq NaOH)
Toxicity data: LD50 i.v. in male mice: 500 mg/kg (Todo)
Derivative Type: Methanesulfonate
CAS Registry Number: 163680-77-1
Additional Names: Pazufloxacin mesylatePercent Composition: C 49.27%, H 4.62%, F 4.58%, N 6.76%, O 27.03%, S 7.74%
Properties: Colorless prisms, mp 258-259°(dec). [a]D20 -64.2° (c = 1 in 1.0N NaOH). Soly (25°) in water 200 mg/ml.
Melting point: mp 258-259°(dec)
Optical Rotation: [a]D20 -64.2° (c = 1 in 1.0N NaOH)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.
产品链接: 127045-41-4››

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