Enoxacin CAS Registry Number: 74011-58-8 依诺沙星

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Literature References: Fluorinated quinolone antibacterial; nalidixic acid analog. Prepn and antibacterial activity: J. Matsumoto et al., EP 9425; eidem, US 4352803; eidem, US 4359578 (1980, 1982, 1982 all to Dainippon and Roger Bellon); J. Matsumoto et al., J. Med. Chem. 27, 292 (1984). HPLC determn in plasma, urine: T. B. Vree et al., J. Chromatogr. 343, 449 (1985). In vitro comparison with other quinolones and azaquinolones: S. Selwyn, M. Bakhtiar, Drugs Exp. Clin. Res. 10, 653 (1984). Pharmacokinetics, therapeutic efficacy: K. G. Naber et al., Infection 13, 219 (1985). Efficacy in treatment of urinary tract infections: R. R. Bailey, B. A. Peddie, N. Z. Med. J. 98, 286 (1985). Toxicology studies: H. Senda et al., Chemotherapy (Tokyo) 32, Suppl. 3, 192 (1984). Series of articles on activity, pharmacology, metabolism, early clinical studies: ibid. 1-1093; J. Antimicrob. Chemother. 14, Suppl. C, 1-96 (1984); on activity, pharmacokinetics, clinical safety and efficacy: Infection 14, Suppl. 3, S183-S220 (1986).