Properties: Colorless needles from ethanol, mp 239-240.5°. Soly at 25° (mg/ml): 1.03 at ionic strength 0.15 M NaCl. uv max (0.15 M acetate buffer, pH 5): 226, 288, 320 nm (aM ´ 10-3 15.5, 36.7, 13.5); uv max (0.05 M phosphate buffer, pH 7): 282, 326 nm (aM ´ 10-3 31.5, 13.3); uv max (0.15 M borate buffer, m = 0.15 M with NaCl, pH 9): 282, 328 nm (aM ´ 10-3 29.3, 13.2). LD50 in mice (mg/kg): 245.6 i.v.; 4000 orally (Itoh).
Melting point: mp 239-240.5°
Absorption maximum: uv max (0.15 M acetate buffer, pH 5): 226, 288, 320 nm (aM ´ 10-3 15.5, 36.7, 13.5); uv max (0.05 M phosphate buffer, pH 7): 282, 326 nm (aM ´ 10-3 31.5, 13.3); uv max (0.15 M borate buffer, m = 0.15 M with NaCl, pH 9): 282, 328 nm (aM ´ 10-3 29.3, 13.2)
Toxicity data: LD50 in mice (mg/kg): 245.6 i.v.; 4000 orally (Itoh)
Derivative Type: Monohydrochloride
CAS Registry Number: 98079-52-8Trademarks: Bareon (Hokuriku); Chimono (Lusofarmaco); Lomebact (Shionogi); Maxaquin (Pharmacia); Okacin (Novartis); Okacyn (Novartis)
Percent Composition: C 52.65%, H 5.20%, F 9.80%, N 10.84%, O 12.38%, Cl 9.14%
Properties: Colorless needles from water, mp 290-300° (dec).
Melting point: mp 290-300° (dec)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.
产品链接: 98079-51-7››