Ronifibrate CAS Registry Number: 42597-57-9 罗尼贝特
CAS Name: 3-Pyridinecarboxylic acid 3-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]propyl ester
Additional Names: 3-(nicotinoyloxy)propyl p-chlorophenoxyisobutyrate; 3-[a-(p-chlorophenoxy)isobutyryloxy]propyl nicotinateTrademarks: Cloprane (Luitpold)
Percent Composition: C 60.40%, H 5.34%, Cl 9.38%, N 3.71%, O 21.17%
📌 参考资料/链接：
Literature References: Diester of clofibric and nicotinic acids, q.q.v. Prepn: Y. Hirata et al., JP Kokai 73 40777 (1973 to Yamanouchi), C.A. 79, 66180w (1973); H. Shindo et al., JP Kokai 74 30377 (1974 to Kowa Pharm.), C.A. 81, 135984s (1974). Clinical trial in hyperdyslipidemia: A. Bucalossi et al., Clin. Ter. 89, 127 (1979). Efficacy and tolerability: G. Buzzelli et al., ibid. 251.
📄 详细内容
Properties: LD50 orally in mice: 4.08 g/kg (Bucalossi).
Toxicity data: LD50 orally in mice: 4.08 g/kg (Bucalossi)
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Fibrates.
产品链接: 42597-57-9››