Acoziborole CAS# 1266084-51-8 4-氟-N-(1-羟基-3,3-二甲基-1,3-二氢苯并[C][1,2]噁硼戊环-6-基)-2-(三氟甲基)苯甲酰胺
Acoziborole, also known as SCYX-7158 is an orally-active compound with potent antitrypanosoma activity for the potent treatment of stage 2 human African trypanosomiasis. Human African trypanosomiasis (HAT, better called as sleeping sickness), caused by two morphologically identicalprotozoan parasite Trypanosoma bruceiis transmitted by the bite of tsetse flies of Glossinagenus, mainly in the rural areas of the sub-Saharan Africa.
📌 参考资料/链接:
Benzoxaboroles: a new class of potential drugs for human African trypanosomiasisBy: Jacobs, Robert T.; et alFuture Medicinal Chemistry (2011), 3(10), 1259-1278
📄 详细内容
CAS No. 1266084-51-8 4-氟-N-(1-羟基-3,3-二甲基-1,3-二氢苯并[C][1,2]噁硼戊环-6-基)-2-(三氟甲基)苯甲酰胺Acoziborole synthetic routes

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasisBy: Jacobs, Robert T.; et alFuture Medicinal Chemistry (2011), 3(10), 1259-1278
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