网站主页>>>数据中心>>>工艺路线数据>>>Plazomicin CAS# 1154757-24-0 (2S)-4-氨基-N-(1R,2S,3S,4R,5S)-5-氨基-4-{(2S,3R)-3-氨基-6-{(2-羟基乙基)氨基甲基}-3,4-二氢-2H-吡喃-2-酰氧基}-2-{(2R,3R,4R,5R)-3,5-二羟基-5-甲基-4-(甲基氨基)氧杂烷-2-yloxy}-3-羟基环己基-2-羟基丁酰胺
Plazomicin CAS# 1154757-24-0 (2S)-4-氨基-N-(1R,2S,3S,4R,5S)-5-氨基-4-{(2S,3R)-3-氨基-6-{(2-羟基乙基)氨基甲基}-3,4-二氢-2H-吡喃-2-酰氧基}-2-{(2R,3R,4R,5R)-3,5-二羟基-5-甲基-4-(甲基氨基)氧杂烷-2-yloxy}-3-羟基环己基-2-羟基丁酰胺
Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin demonstrates high activity against the Enterobacteriaceae including extended spectrum beta lactamase and most carbapenemase producers, and can be useful in treating complicated urinary tract infections (cUTIs) and acute pyelonephritis. It is undergoing Phase III clinical studies.
📌 参考资料/链接：
Reference: Ma, Shutao; Cai, Xiaokang. Method for preparing plazomicin antibiotic for bacterial infection. Assignee Shandong University, Peop. Rep. China. CN 108948107. (2018).
Reference: Ma, Shutao; Cai, Xiaokang. Method for preparing plazomicin antibiotic for bacterial infection. Assignee Shandong University, Peop. Rep. China. CN 108948107. (2018).
📄 详细内容
CAS No. 1154757-24-0 (2S)-4-氨基-N-(1R,2S,3S,4R,5S)-5-氨基-4-{(2S,3R)-3-氨基-6-{(2-羟基乙基)氨基甲基}-3,4-二氢-2H-吡喃-2-酰氧基}-2-{(2R,3R,4R,5R)-3,5-二羟基-5-甲基-4-(甲基氨基)氧杂烷-2-yloxy}-3-羟基环己基-2-羟基丁酰胺Plazomicin synthetic routes
Ma, Shutao; Cai, Xiaokang. Method for preparing plazomicin antibiotic for bacterial infection. Assignee Shandong University, Peop. Rep. China. CN 108948107. (2018).
产品链接: CAS No. 1154757-24-0 ››
Ma, Shutao; Cai, Xiaokang. Method for preparing plazomicin antibiotic for bacterial infection. Assignee Shandong University, Peop. Rep. China. CN 108948107. (2018).
产品链接: CAS No. 1154757-24-0 ››