A-1293201 CAS# 1375557-33-7
A-1293201 is a potent and selective NAMPT inhibitor. A-1293201 binds to NAMPT and inhibits its enzymatic activity.
📌 参考资料/链接：
1.1Solvents:Tetrahydrofuran;0 °C → rt; overnight, rt2.1Reagents:Lithium hydroxideSolvents:Methanol,Tetrahydrofuran,Water;> 1 d, rt2.2Reagents:Hydrochloric acidSolvents:Water;pH 3, rt3.1Reagents:1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride,1-Hydroxy-1H-benzotriazole hydrate (1:?)Solvents:Dimethylformamide;overnight, rt4.1-
1.1Solvents:Tetrahydrofuran;0 °C → rt; overnight, rt2.1Reagents:Lithium hydroxideSolvents:Methanol,Tetrahydrofuran,Water;> 1 d, rt2.2Reagents:Hydrochloric acidSolvents:Water;pH 3, rt3.1Reagents:1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride,1-Hydroxy-1H-benzotriazole hydrate (1:?)Solvents:Dimethylformamide;overnight, rt4.1-
📄 详细内容
CAS No. 1375557-33-7 A-1293201 synthetic routes
Dihydroisoindolecarboxamide derivatives as NAMPT and ROCK inhibitors and their preparationAssignees: Abbott Laboratories; AbbVie Inc.Inventors: Curtin, Michael L.; et alUnited StatesPatent#US20120122842 A1
产品链接: CAS No. 1375557-33-7 ››
Dihydroisoindolecarboxamide derivatives as NAMPT and ROCK inhibitors and their preparationAssignees: Abbott Laboratories; AbbVie Inc.Inventors: Curtin, Michael L.; et alUnited StatesPatent#US20120122842 A1
产品链接: CAS No. 1375557-33-7 ››