Tafenoquine CAS# 106635-80-7 他非诺喹
Tafenoquine, also known as WR-238605, is an oral active antimalaria drug that is being investigated as a potential treatment for malaria, as well as for malaria prevention. Tafenoquine Shows Activity against Trypanosoma brucei. Tafenoquine targets leishmania respiratory complex III and induces apoptosis. Tafenoquine has a long half-life of approximately 14 days and is generally safe and well tolerated, Malaria remains an important cause of global morbidity and mortality. As antimalarial drug resistance escalates, new safe and effective medications are necessary to prevent and treat malarial infection.
📌 参考资料/链接：
Reference: Blumbergs, Peter; LaMontagne, Maurice P. 4-Methyl-5-[(un)substituted phenoxy]-2,6-dimethoxy-8-(aminoalkylamino)quinolones. Assignee United States Dept. of the Army, USA. US 4617394. (1986).
Reference: Blumbergs, Peter; LaMontagne, Maurice P. 4-Methyl-5-[(un)substituted phenoxy]-2,6-dimethoxy-8-(aminoalkylamino)quinolones. Assignee United States Dept. of the Army, USA. US 4617394. (1986).
📄 详细内容
CAS No. 106635-80-7 他非诺喹Tafenoquine synthetic routes
Blumbergs, Peter; LaMontagne, Maurice P. 4-Methyl-5-[(un)substituted phenoxy]-2,6-dimethoxy-8-(aminoalkylamino)quinolones. Assignee United States Dept. of the Army, USA. US 4617394. (1986).
产品链接: CAS No. 106635-80-7 ››
Blumbergs, Peter; LaMontagne, Maurice P. 4-Methyl-5-[(un)substituted phenoxy]-2,6-dimethoxy-8-(aminoalkylamino)quinolones. Assignee United States Dept. of the Army, USA. US 4617394. (1986).
产品链接: CAS No. 106635-80-7 ››