Belinostat CAS# 866323-14-0 贝利司他
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase. Belinostat was approved in 2014 for relapsed or refractory peripheral T-cell lymphoma.
📌 参考资料/链接：
Bao, Xuefei; Song, Dake; Qiao, Xuejun; Zhao, Xuan; Chen, Guoliang. The development of an effective synthetic route of belinostat. Organic Process Research & Development. Volume 20. Issue 8. Pages 1482-1488. Journal; Online Computer File. (2016).
Bao, Xuefei; Song, Dake; Qiao, Xuejun; Zhao, Xuan; Chen, Guoliang. The development of an effective synthetic route of belinostat. Organic Process Research & Development. Volume 20. Issue 8. Pages 1482-1488. Journal; Online Computer File. (2016).
📄 详细内容
CAS No. 866323-14-0 贝利司他Belinostat synthetic routes
Bao, Xuefei; Song, Dake; Qiao, Xuejun; Zhao, Xuan; Chen, Guoliang. The development of an effective synthetic route of belinostat. Organic Process Research & Development. Volume 20. Issue 8. Pages 1482-1488. Journal; Online Computer File. (2016).
产品链接: CAS No. 866323-14-0 ››
Bao, Xuefei; Song, Dake; Qiao, Xuejun; Zhao, Xuan; Chen, Guoliang. The development of an effective synthetic route of belinostat. Organic Process Research & Development. Volume 20. Issue 8. Pages 1482-1488. Journal; Online Computer File. (2016).
产品链接: CAS No. 866323-14-0 ››