Deferiprone CAS# 30652-11-0 去铁酮
Deferiprone is a drug that chelates iron and is used to treat thalassaemia major. In 1994 was first approved for use in treating thalassaemia major in 1994 and had been licensed for use in Europe and Asia for many years while awaiting approval in Canada and the United States. On October 14, 2011, it was approved for use in the US under the FDAÂ’s accelerated approval program.
📌 参考资料/链接：
Dobbin, Paul S.; Hider, Robert C.; Hall, Adrian D.; Taylor, Paul D.; Sarpong, Patience; Porter, John B.; Xiao, Gaoyi; van der Helm, Dick. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. Journal of Medicinal Chemistry. Volume 36. Issue 17. Pages 2448-58. Journal. (1993).
Dobbin, Paul S.; Hider, Robert C.; Hall, Adrian D.; Taylor, Paul D.; Sarpong, Patience; Porter, John B.; Xiao, Gaoyi; van der Helm, Dick. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. Journal of Medicinal Chemistry. Volume 36. Issue 17. Pages 2448-58. Journal. (1993).
📄 详细内容
CAS No. 30652-11-0 去铁酮Deferiprone synthetic routes
Dobbin, Paul S.; Hider, Robert C.; Hall, Adrian D.; Taylor, Paul D.; Sarpong, Patience; Porter, John B.; Xiao, Gaoyi; van der Helm, Dick. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. Journal of Medicinal Chemistry. Volume 36. Issue 17. Pages 2448-58. Journal. (1993).
产品链接: CAS No. 30652-11-0 ››
Dobbin, Paul S.; Hider, Robert C.; Hall, Adrian D.; Taylor, Paul D.; Sarpong, Patience; Porter, John B.; Xiao, Gaoyi; van der Helm, Dick. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. Journal of Medicinal Chemistry. Volume 36. Issue 17. Pages 2448-58. Journal. (1993).
产品链接: CAS No. 30652-11-0 ››