Darunavir CAS# 206361-99-1 地瑞拉韦
Darunavir is a drug used to treat HIV infection. It is in the protease inhibitor class. Prezista is an OARAC recommended treatment option for treatment-naïve and treatment-experienced adults and adolescents. Developed by pharmaceutical company Tibotec, darunavir is named after Arun K. Ghosh, the chemist who discovered the molecule at the University of Illinois at Chicago. It was approved by the Food and Drug Administration (FDA) on June 23, 2006. .
📌 参考资料/链接:
Ghosh, Arun K.; Leshchenko, Sofiya; Noetzel, Marcus. Stereoselective Photochemical 1,3-Dioxolane Addition to 5-Alkoxymethyl-2(5H)-furanone: Synthesis of Bis-tetrahydrofuranyl Ligand for HIV Protease Inhibitor UIC-94017 (TMC-114). Journal of Organic Chemistry. Department of Chemistry. University of Illinois at Chicago. Chicago, USA 60607. Volume 69. Issue 23. Pages 7822-7829. 2004
📄 详细内容
CAS No. 206361-99-1 地瑞拉韦Darunavir synthetic routes

Ghosh, Arun K.; Leshchenko, Sofiya; Noetzel, Marcus. Stereoselective Photochemical 1,3-Dioxolane Addition to 5-Alkoxymethyl-2(5H)-furanone: Synthesis of Bis-tetrahydrofuranyl Ligand for HIV Protease Inhibitor UIC-94017 (TMC-114). Journal of Organic Chemistry. Department of Chemistry. University of Illinois at Chicago. Chicago, USA 60607. Volume 69. Issue 23. Pages 7822-7829. 2004
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